Every day, we are surrounded by hundreds or thousands of synthetic chemicals. They are in our food, clothes, tools, furniture, toys, cosmetics and medicines. Our society would not be the same without these substances. However, despite their usefulness, we know many of these substances can have negative impacts on our health and the environment. The chemical signature of humans is now ubiquitous and has been detected in the upper atmosphere, on the highest mountains, in the deepest oceans, from pole to pole and in the most remote, uninhabited regions, in soil, water, air, and in the human food chain. 350,000 chemical substances have been registered for large scale use over the past 30 years. About 700 new chemicals per year are officially added to the US Toxic Substances Control Act (TSCA) inventory each year, while the European Chemicals Agency has registered about 1700 (new and existing substances) per year since 2009. Of the 100,000 chemicals that have at least limited toxicity information available, less than one-fifth also have exposure information, meaning they are not frequently measured in the water, soil, and air. We've invited Seed co-founder Raja Dhir to chat in conversation with physician/author Dr. James Hamblin about environmental toxins and their impact on human and planetary health.