This talk explores how combining senolytics, NAD+ boosters, and synbiotics can form a powerful age-better strategy by addressing key mechanisms of aging. It highlights how aging-related cellular damage, including the accumulation of senescent cells and the decline in NAD+ levels, leads to decreased resilience. By targeting these hallmarks of aging, such as genomic instability and mitochondrial dysfunction, this approach offers a comprehensive solution for healthier aging. Attendees will learn how senolytics, NAD+ boosters and synbiotics work together to enhance energy metabolism, eliminate harmful senescent cells, and support gut health for a longer, healthier life.